I used to live literally 50 yards from your hotel. Look out the window, you'll see my back garden!
There's not much in the immediate vicinity but you have a few options...
If you like curry, go to Rusholme, Wilmslow Road - the world famous Curry Mile. AMAZING!
If you like pub food head down to Didsbury to The Didsbury (or, next door is a Loch Fyne if you're feeling flush - it's very good).
If you like exciting noodly things, try Fuzion in Fallowfield - fantastic VFM, we used to go there about once a fortnight!
If you like normal Nando/Chiquito/Frankie & Benny's type food, go out to the M60 and go up one junction to J23. On Ashton Court Retail park there are all the above, plus a Chinese buffet which I haven't tried.
Or, head into the middle of town - regular buses from Hyde Road, get a 201/203/204.