Partner never rides bikes (only horses) so when go away with the bikes it's like she's not ridden further than the pub in a year or more
I bought the best bike that I thought would do everything which turned out to be a near new Spesh Globe Pro.
CF rear stays/Forks & Seatpost offered good vibration damping, minute adjustments to stem length & bar width (56cm Syncros EA70 flat) paying a fair bit of attention not to push her too forward so lesser amount of pressure on the wrists/shoulders got her in a very comfy natural position.
Tyres are 700x42 Spesh borough folders which are fast rolling & quite light yet offer good puncture protection and comfort in spades.
The stock Spesh Ladies sportourer saddle she reckons is bob on, even slim ladies have wide sit bones and do require something wider than a men's saddle. I reckon a Rolls probably isn't wide enough but saddles are such a funny thing and you nevercan tell until you've done any distance on them tbh.
Cranks are std Deore 175mm, she's 5ft 5 and finds them fine and rides standard flat cage pedals & no padded shorts.
With a massive range of gears from the 48/36/26 & 11-32 cassette she can get up some pretty steep inclines and do 45 miles straight off the bat without blinking and she's over 40 (sorry hun

) and of average fitness but determined when she wants to be. I reckon she could do a ton in a day if she chose to do so
I think getting the absolute perfect position without stressing shoulders/wrists & plenty of low down gears has to be the starting point.
Here's the bike before I got rid of the ugly S-Works CF bars & change of stem.
Even with the rackpack & bog std wheels it is 11.5kg