Another vote for yes, the ride is VERY different bike to bike.
Some bikes are very stiff, they crack along at a fair rate and are good climbers, but that stiffness makes them slower on rough downhills, as if you push them, they will kick you up the ar$se. Others are smooth and compliant, the Lloyd CATS WISKAS that Ringo has is an amazing frame that really encourages you to push as hard as you can on all terrain. Others like the DOGS BOLX are well balanced, real go anywhere do anything bikes; the list of differences is almost endless, as are the types of tubing used and the combinations they are used in.