Re:
Thanks everyone very much for the ideas. Everything is taking ten times longer than before but I now have an almost complete, one-arm-built, left hand controlled retrobike!
I think I found probably the most straightforward way, Di2 aside (I couldn't on a retrobike even if it was no expense spared).
The Paul Duplex brake lever pulls two cables simultaneously and can be mounted left or right - it was invented for bike polo apparently, brilliant. Independent adjustment is then a matter of cable tension. The shifters are just Shimano ten speed thumbies, designed for road mechanisms not mtb, with the rear mounted upside down. You can probably see that the only problem looks like water would get in at the silver lever, but dry days only for me anyway. The upshot is everything can be done without taking the good hand off the bars, possibly an advantage over bar-ends.
Straight bars for the mounting diameters of the clamps but otherwise no compromises (apart from 10 speed if that counts). More piccies when it's done - need to get a fork painted.